Tulane Center for Stem Cell Research and Regenerative Medicine

Established in 2008 at Tulane University School of Medicine, the Tulane Center for Stem Cell Research and Regenerative Medicine is dedicated to pioneering adult stem cell therapies, emphasizing adipose-derived mesenchymal stem cells (MSCs) and bone marrow stromal cells for regenerative applications. The center integrates basic research, preclinical modeling, and clinical translation to develop safe, effective treatments for a wide array of conditions, from orthopedic injuries and cardiovascular disease to neurological disorders and cancer.

Driven by Tulane’s tripartite mission of education, research, and patient care, the center fosters interdisciplinary collaboration among faculty from structural & cellular biology, orthopedics, pharmacology, and beyond, creating programs of excellence in regenerative medicine. It supports graduate training, seminars, and shared resources while prioritizing ethical stem cell use and rapid bench-to-bedside translation.

Research Focus & Achievements:

The center specializes in adipose and bone marrow-derived stem cells, exploring their multipotent differentiation into adipocytes, chondrocytes, osteoblasts, neurons, and hematopoietic supporters. Key areas include inflammation modulation, angiogenesis for ischemic tissues, cartilage regeneration (e.g., via DCX protein mechanisms), and ex vivo processing for one-hour autologous cell therapies without culturing. Facilities support GMP-like production, high-throughput screening, and biomaterial integration for organ regeneration.

Notable milestones include decades of work on naturally occurring regenerative cells from fat tissue, leading to publications on their potential for next-generation therapies (highlighted in 2025 reviews). Collaborations span MD Anderson, Methodist Research Center, and international partners, with ongoing NIH-funded projects in stem cell preconditioning, bioreactors, and clinical outcomes for revascularization. As of 2025, the center contributes to Tulane’s bioinnovation initiatives, including biosensors and advanced therapeutics, while training fellows in translational delivery systems.

Backed by state grants, NIH, and institutional support, the center bridges gaps in regenerative medicine, emphasizing minimally manipulative, point-of-care approaches.